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Alcohol & Drug Rehab Centers in Mississippi

Mississippi offers a wide range of addiction treatment options. This guide covers some of the best alcohol and drug rehab centers in Mississippi, including programs in Biloxi, Southaven, and Brandon. Our team identified 5 reputable rehab centers in Mississippi that provide services from medical detox to residential treatment and outpatient programs.

Content review by Tariq M. Ghafoor, M.D. Board-Certified Addiction Psychiatrist

Last updated on February 28, 2026

This page’s clinical overview has been medically reviewed by a U.S.-licensed psychiatrist to ensure accurate, ethical, and up-to-date information about addiction treatment in Mississippi. This review does not apply to individual facilities listed on this page and does not replace professional medical care.

Mississippi Drug and Alcohol Treatment Center rehab in Biloxi, MS

Mississippi Drug and Alcohol Treatment Center

Google Logo 4.6
(84 reviews)

A family-owned, 16-bed facility in Biloxi, MS, offering a full continuum of care for substance use and co-occurring disorders, with a specialized program for military veterans.

Biloxi, MS

Levels of Care:

Inpatient Detox Inpatient/Residential Outpatient (IOP/PHP)
Woodland Recovery Center

Woodland Recovery Center

Google Logo 4.5
(326 reviews)

Mississippi's evidence-based addiction treatment center offering a full continuum of care, including detox, residential, and outpatient services, with specialized tracks for Veterans and LGBTQIA+.

Southaven, MS

Levels of Care:

Inpatient Detox Inpatient/Residential Outpatient (IOP/PHP)

Navigating Treatment Options in Mississippi

Understanding the different levels of care is the first step. Mississippi offers a full spectrum of programs to meet you where you are in your recovery journey.

Medical Detox

A safe, medically supervised process to manage withdrawal symptoms. This is often the necessary first phase before beginning a therapeutic program.

Inpatient / Residential

A highly structured, 24/7 live-in program providing an immersive, substance-free environment ideal for focusing completely on recovery without outside triggers.

Outpatient (PHP/IOP)

Flexible programs that allow you to live at home while attending scheduled therapy sessions, helping you integrate recovery skills into daily life.

This information is for educational purposes only and is not a substitute for medical advice or evaluation. If you are in crisis, call 988 or go to the nearest emergency room.

Defining Wellness Centers

Defining Wellness Centers

Google Logo 4.7
(178 reviews)

A luxury addiction treatment facility in Mississippi offering detox, residential, and IOP on a serene 26-acre campus with holistic therapies.

Brandon, MS

Levels of Care:

Inpatient Detox Inpatient/Residential Outpatient (IOP/PHP)
The Estate at Riverbend

The Estate at Riverbend

Google Logo 4.4
(94 reviews)

A premier dual diagnosis and addiction treatment center in Mississippi, located on a 108-acre campus, offering medical detox, residential, and PHP programs with housing for adults and veterans.

Lucedale, MS

Levels of Care:

Inpatient Detox Inpatient/Residential Outpatient (IOP/PHP)

Our Vetting Process & Ethical Promise

Your trust is our priority. We are an independent resource committed to providing accurate and ethical information. We do not engage in patient brokering, and our listings are curated based on strict criteria to ensure quality and safety.

  • Licensing & Accreditation: We verify that facilities hold current state licenses and reputable accreditations (e.g., JCAHO, CARF).
  • Evidence-Based Practices: We prioritize centers that use scientifically-backed therapeutic methods.
  • Ethical Marketing: We ensure facilities adhere to transparent and honest marketing practices.

This information is for general educational purposes and does not imply endorsement of any specific treatment center. If you are in crisis, call 988 or go to the nearest emergency room.

Stonewater Adolescent Recovery Center

Stonewater Adolescent Recovery Center

Google Logo 4.8
(64 reviews)

Specialized treatment for teen boys with substance abuse and co-occurring disorders on a 65-acre campus in Mississippi. Offers detox and residential programs.

Oxford, MS

Levels of Care:

Inpatient Detox Inpatient/Residential Teens/Adolescents Men Only

Frequently Asked Questions – Mississippi Rehab

How do I pay for rehab in Mississippi?

Many rehab centers in Mississippi accept private insurance, self-pay, and payment plans. Some facilities accept Mississippi Medicaid, which may cover detox, inpatient rehab, outpatient treatment (PHP/IOP), and medication-assisted treatment (MAT) when medically necessary. If you are uninsured or underinsured, you may qualify for state-funded treatment services through the Mississippi Department of Mental Health (DMH). Always request a free insurance verification to confirm your coverage, deductibles, and expected out-of-pocket costs before beginning treatment.

How do I find a rehab near me in Mississippi?

To find a rehab near you in Mississippi, search by city or region such as Jackson, Gulfport, Biloxi, Hattiesburg, or Tupelo. Compare programs based on level of care (medical detox, residential rehab, outpatient services), insurance accepted, and admission availability. You can also call Mississippi’s mental health crisis line at 1-877-210-8513 or dial 988 for 24/7 mental health or substance use crisis support statewide.

What is the difference between inpatient and outpatient rehab in Mississippi?

Inpatient rehab in Mississippi (residential treatment) requires you to live at the facility full-time with structured therapy and 24/7 clinical supervision. This level of care is often recommended for individuals with severe substance use disorders or co-occurring mental health conditions. Outpatient rehab in Mississippi allows you to live at home while attending scheduled treatment sessions several times per week. Many outpatient programs include medication-assisted treatment (MAT), counseling, group therapy, and relapse prevention services while allowing you to maintain work or family responsibilities.

Why choose Mississippi for addiction treatment?

Mississippi offers community-based addiction treatment programs throughout the state, with options available in both urban and rural areas. Many facilities focus on evidence-based care and faith-based recovery options, reflecting the state’s strong community values. Staying in-state for rehab can make it easier to transition into Mississippi-based outpatient programs, sober living homes, and long-term recovery support after completing residential treatment.

What should I bring with me to rehab in Mississippi?

Bring 5–7 days of comfortable clothing and weather-appropriate layers (Mississippi summers can be hot and humid). Pack alcohol-free toiletries, a government-issued ID, your insurance card (including Mississippi Medicaid if applicable), and prescribed medications in their original pharmacy bottles. Most Mississippi rehab centers provide a detailed packing list before admission. Leave valuables, unapproved electronics, and non-prescribed substances at home.

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